Why is Ozone Therapy Useful For So Many Different Diseases?
The use of ozone gas as a therapy in the health field has attracted some skepticism due to its unstable molecular structure. However, ozone therapy has been researched in-depth pertaining to its biochemistry, physiological and pharmacological knowledge and effect. Literature has shown that ozone is highly valued for various effects, such as being antimicrobial, anti-hypoxic, analgesic, immune modulating etc. on various biological systems.
- Infectious diseases (bacterial, viral, fungal and parasitic)
- HIV-1 infection
- Chronic Hepatitis B and C
- Herpetic infections and Herpes Zoster
- Colds and flus
- Dysmetabolic syndrome
- Ischemic diseases
- Retinal degenerative disorders
- Neurodegenerative diseases
- Autoimmune diseases
- Overuse of antibiotics or antibiotic resistance
- Dermatological diseases
- Pulmonary diseases
- Chronic fatigue syndrome and fibromyalgia
- Emergency situations, pre and post-surgery
- Dentistry and oral medicine
The question is, why?
Ozone (O3) is an unstable oxidizing molecule consisting of three oxygen atoms. Some of you may have heard that ozone is toxic for inhalation and there are numerous cases describing its detrimental effects. This statement is true. Our alveolar surface in the lungs is protected by a small amount of antioxidant content, which is insufficient in extinguishing the strong oxidant activity of ozone. In other words, your lungs simply don’t have enough antioxidants to deal with the potent power of this oxidative therapy.
Nevertheless, the exact opposite is true for our blood and internal components as both our plasma and blood cells have a remarkable quantity of cooperating antioxidants. When administered ozone reacts within seconds with the organic components such as cells, blood, viruses, bacteria etc. and generates a number of chemical messengers responsible for activating crucial biological functions.
What are these crucial biological functions?
1. Ozone increases oxygenation
Ozone has demonstrated its effect in the regulation of the oxygen metabolism and oxygenation. When administered, ozone increases the content of free dissolved blood oxygen – resulting in production of energy and re-establishing the normal metabolic functions. Ozone improves systemic oxygenation by significantly and constantly increasing oxygen availability and microcirculation. In regards to cancer, ozone mediated hyperoxia (refers to a state of sufficient oxygen) inhibits and counteracts the hypoxia inducing factor therefore reducing angiogenesis and improving radiotherapy and chemotherapy.
2. Ozone improves antioxidant systems
In response to ozone a mild – moderate oxidative stress occurs which activates Nrf2. Nrf2 then induces the transcription of antioxidant response elements resulting in the production of antioxidant enzymes including – superoxide dismutase (SOD), catalase and glutathione peroxidase. Both these free and antioxidant enzymes not only protect from oxidation and inflammation but they can reverse chronic oxidative stress.
3. Ozone improves energy levels
Ozone therapy increases ATP production. It is also a powerful mitochondrial stimulant. Under conditions of stress or growth factor stimulation, activation of Nrf2 counteracts the increased reactive oxygen species production in mitochondria. Any Nrf2 activator, was found to promote mitophagy, thereby contributing to the overall mitochondrial homeostasis.
4. Ozone is anti-inflammatory
Inflammation is induced via NFκB activation by various inflammatory factors such as severe oxidative stress. Antioxidants and anti-oxidative enzymes not only protect cells from oxidation and inflammation but they may be able to reverse the chronic oxidative stress. Ozone therapy activates Nrf2 via moderate oxidative stress, and suppresses NFκB and inflammatory responses.
5. Ozone is anti-bacterial, anti-viral and anti-fungal
Ozone therapy produces a direct oxidative effect on bacteria, viruses, fungi and protozoa. This oxidative effect has a damaging consequence on the microorganism’s membrane.
Ozone interferes with the metabolism of bacterium-cells, through inhibition and by blocking the operation of the enzymatic control system. A sufficient amount of ozone breaks through the cell membrane, and this results in the destruction of the bacteria. Indirectly this activates the immune response. Unlike bacteria, viruses multiply only within the host cell. They transform protein of the host cell into proteins of their own. Ozone destroys viruses by diffusing through the protein coat into the nucleic acid core which results in viral RNA damage. At higher concentrations, ozone affects the DNA structures of the microorganism.
6. Ozone is analgesic
“The analgesic effect of ozone is provided by oxidation of the products of albuminolysis, the so-called lgopeptides that act on the nerve endings in the damaged tissue and determine the intensity of pain response”. In addition to that, analgesic effects are also caused by a normalization of the antioxidant system, a reduction in inflammation and improved oxygenation.
7. Ozone supports detoxification
8. Ozone improves elasticity of red blood cells
Ozone can decrease the thickness and viscosity of blood that would make it easier for circulation and also stimulate dilation and relaxation of the artery walls. It was observed that ozone had a statistically significant decrease in plasma total cholesterol and low-density lipoprotein. Ozone reduces platelet aggregation and makes red blood cells more elastic and flexible.
9. Ozone immune modulating effects
When addressing disease, it is important to identify the root cause resulting in ill health. To do this effectively, it requires an individualized approach to understand each person’s unique genetic, biochemical and lifestyle factors. The causes of a disease vary from person to person however several general components which ozone address are often implicated:
- Poor oxygenation and circulation
- Mitochondrial function
- Low antioxidant status
Additionally, other causes are implicated in disease including but not limited to: unhealthy diet, poor lifestyle choices, stress and trauma, deficiencies, specific organ weakness, dental hygiene, DNA impairments, acidity and alkalinity.
In almost all disease states the crucial biological functions that ozone provides have a beneficial result. Ozone covers multiple aspects within the one therapy which is why it is such a favorable choice. Furthermore, ozone therapy is systemic providing an effect on the whole body. In saying that, ozone therapy is not the cure you’ve been looking for but rather a powerful adjunct therapy and prevention tool for many conditions. Ultimately, removing the root cause of disease is imperative to ensure long lasting health, prevention and re-occurrence.
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