Log in to the TRULY HEAL APP     -     1-800-810-4796 - USA/Canada Toll Free

Are YOU afraid of using OZONE?

We’ve all heard of the ozone layer (naturally produced) in the stratosphere, which resides roughly 10-15 kilometers above the Earth’s surface. This 10 inch thick  layer of gas is vital for life on Earth as it absorbs the sun’s ultraviolet radiation. However man-made chemicals referred to as ozone-depleting substances are slowly destroying this important layer of ozone. But that’s not the topic of today’s article. It is just a means to warm you up to the idea that without Ozone there would be no life on earth.

Ozone is also produced when pollutants emitted by cars, power plants, chemical plants, industrial boilers and other sources react chemically in the presence of sunlight. This ozone is harmful to breathe and it damages crops, trees and, other vegetation. But when you look closely Ozone is the natural cleaning process the earth has created to clean air of pollutants. The unstable form of Ozone dissolves immediately when the job is done.

“How can ozone be dangerous but also considered an effective treatment for some of humanities most threatening diseases?”

In this first chapter I would like to explain why ozone is toxic for inhalation.
It's because in humans the great expanse of our alveolar surface is protected by a small amount of antioxidant content, which is insufficient in extinguishing the strong oxidant activity of ozone. Your lungs simply have not enough antioxidants to deal with the potent power of this oxidative therapy.

That's why breathing ozone in larger concentrations is harmful to the human being.

The exact opposite is true for our blood because both the plasma and blood cells have a remarkable quantity of cooperating antioxidants.

The tiny amount of ozone that is induced during therapy triggers in healthy cells a moderate oxidative stress when interacting with lipids (found in our body and cells). This tiny stress triggers a host of reactions.

  • It increases endogenous production of antioxidants,
  • activates our Nrf2 pathway,
  • decreases inflammation,
  • improves circulation and oxygen delivery to cells
  • and enhances our immune system.

Unhealthy cells (infected, toxic and diseases cells) that get in contact with ozone simply die. So do all pathogens like bacteria, virus, candida, yeast and fungi.

Despite all the research and lifetimes of evidence it has become obvious that Big Pharma controlled countries neglect the use of ozone in medicine because it's cheap, they don't earn a cent of it's use and because it poses a threat to the vast amount of drugs that have a fraction of the efficiency and a host of side effects.

Ozone History

Christian Friedrich Schonbein a German chemistry professor first discovered ozone in the late 18th century. It was first used to disinfect operating rooms in 1856 and subsequently for disinfecting water in 1860. Ozone has very unique properties, and all microbes are susceptible to its oxidizing abilities. During World War I (1914-1918) the German army used ozone to treat battle wounds and other infections.

Many physicians and clinics all over the world offer ozone therapy and in the past decade this therapy has gained more credibility and prominence. Today medical use of ozone is common throughout Europe (specifically Germany and Eastern Europe), Mexico, Cuba, Dominican Republic and Bahamas. Ozone therapy is gradually increasing in Canada and USA. There are over 40 international organizations representing thousands of practitioners who use ozone in their practice.

Health Conditions That Can Benefit From Ozone

  • Abscesses
  • Acne
  • AIDS
  • Hepatitis
  • Allergies
  • Anal fissures
  • Arthritis
  • Asthma
  • Bacterial, viral, fungal infections
  • Cancer
  • Skin conditions
  • Circulatory disturbances
  • Heart disease
  • Infectious diseases
  • Cirrhosis of liver
  • Constipation
  • Ulcers
  • Fungal diseases
  • Gastro duodenal ulcers
  • Crohn’s disease
  • Ulcerative colitis
  • IBS & IBD
  • Glaucoma
  • Peripheral neuropathy
  • Herpes simplex
  • Hypercholesterolemia
  • Parkinson’s disease
  • Raynaud’s disease
  • Diabetes
  • Depression
  • Chronic fatigue
  • Rheumatoid arthritis
  • Dementia
  • Sinusitis
  • Wound healing
  • Vaginal infections
  • Lyme disease
  • Ear infections
  • Dental issues
  • Chronic pain
  • AND MORE!!!

Beneficial Properties Of Ozone

Ozone has several incredible properties that account for its many clinical uses:

  • Ozone therapy activates Nrf2 pathway (is the master regulator of the cellular antioxidant response)
  • Ozone increases our most potent radical scavenger and cell wall protectors: glutathione peroxidase, catalase and superoxide dismutase.
  • Ozone is highly antimicrobial. Ozone therapy disrupts the integrity of the bacterial cell envelope through oxidation of the phospholipids and lipoproteins. In fungi, O3 inhibits cell growth at certain pivotal stages. And lastly with viruses O3 damages the viral capsid and upsets the reproductive cycle by disrupting the virus-to-cell contact with peroxidation.
  • Ozone therapy causes an increase in the red blood cell glycolysis rate.
  • Ozone leads to an increase in the amount of oxygen released to the tissues. This also results in improved circulation.
  • Ozone activates the citric acid cycle by enhancing oxidative carboxylation of pyruvate, stimulating production of ATP (which is energy).
  • Ozone therapy activates the immune system. O3 increases the production of interferon and the greatest output of tumor necrosis factor and interleukin-2. The production of interleukin-2 launches an entire cascade of subsequent immunological reactions.
  • Ozone therapy stimulates the neuroendocrine system and therefore produces a feeling of well-being.
  • Ozone therapy combats ageing.
  • Ozone therapy decreases inflammation through the activation of Nrf2 and subsequently the suppression of NFkB (pro-inflammatory signaling pathway)

How is it possible that something so effective and inexpensive to treat so many diseases is completely unknown for its health benefits? Well, the answer is simple… ozone therapy is inexpensive and cannot be patented. Therefore, it is suppressed.

How Can Ozone Be Used?

Ozone treatments can be applied in a variety of concentrations, dosage and methods of administration

  1. Major or minor autohemotherapy (mixing ozone with blood and re-infusing)
  2. Direct intra-arterial and intravenous application (ozone slowly injected into an artery or vein)
  3. Intramuscular injection (small amount of ozone usually injected into the buttocks)
  4. Intra-articular injection (ozone is directly injected in-between the joints)
  5. Insufflation (rectal and vaginal – rectal insufflation method is considered one of the safest)
  6. Ozonated water (ozone bubbled through water and used to bathe wounds, burns and skin infections or ingested)
  7. Ozone bagging (sealed area – thus ozone absorbs through the skin, specifically used for slow healing wounds, infections and burns)
  8. Ozone bubbled through olive oil (ozonides are formed by bubbling ozone gas through olive oil)
  9. Ozonated oil (topical application)

Why Are Rectal Insufflations Considered The Best Form Of Administration?

Rectal insufflation of ozone is the easiest and safest form of application and administration. It works systematically without requiring more invasive methods such as autohemotherapy. Not only is it less invasive, easy to do, low cost, painless and practically free of adverse reactions. Rectal insufflations are as effective as major autohemotherapy just require more consistent application. How amazing is this? The best part is that you can do this at home in just a few minutes!! The procedure is usually performed following a bowel movement or a colonic treatment in order to ensure the colon is relatively free of fecal matter.

During rectal insufflations ozone is introduced through a catheter into the colon.  Within 1 to 2 seconds the Ozone has reacted with the bacteria in the mucus membrane and has stimulated a host of biochemical reactions that now activate the healing response Ozone offers to everyone. After about 60-120 seconds the remaining oxygen is absorbed into the system. As a minor reaction of rectal insufflations some patients will feel the need to release gas or defecate.

Ozone Safety & Contraindications 

In spite of the so-called ozone “toxicity”, the incidence of adverse reactions is only 0.000007%, one of the lowest in medicine! Even a Panadol is more harmful and has a lot moreside effects .

It has been confirmed that if ozone is started slowly so that the body is not overwhelmed it is well tolerated by patients. Shortly during and after the procedure, some patients may complain about weakness, slight dizziness, or sleepiness which can be because of the die off of bacteria in the system.

The eyes and lungs are very sensitive to ozone as they have minimal antioxidant and neutralizing capabilities and therefore ozone gas in greater concentrations should never contact eyes and lungs.

Allergic skin reactions are possible, although they are very uncommon. Sifting through literature and studies about skin rashes I found two possible causes. The first possible reason is a Herxheimer reaction (microbial die off).  The other is that individuals with a very low antioxidant status are unable to combat the ozone oxidation until these levels are restored.

Ozone is contraindicated in patients with a significant deficit of Glucose-6-phosphate dehydrogenase deficiency (G-6PD- which is an inherited condition – causing red blood cells to break down in response to certain medication, infections or other stresses). This enzyme provides crucial reducing equivalents able to eliminate excessive oxidation and intensive haemolysis.

Ozone is contraindicated in pregnancy, merely as a precaution. In most European countries pregnant mothers are treated with ozone to provide extra oxygen and immunity to the baby. Also do they treat fresh born babies with ozone to help build a proper gut flora and to combat diseases like allergies, celiac and more which may have transferred from the mother.

Patients being treated with ACE inhibitors should be cautious with ozone and consult a practitioner.

Abnormal situations with hyperthyroidism, thrombocytopenia and serious cardio-vascular instability should also consult a practitioner before commencing with ozone therapy.

This all said most doctors we have interviewed have confirmed that a mild form of rectal insufflation has always helped. Even patients who had all of the above.


Includes: 1 x Ozone Generator with 5 year warranty, 1.5m silicon hose, 1 x International power supply and plugs, 1 Flow Regulator (medical or industrial), 2 x Ozone Insufflation Bags, 10 x Ozone Catheters, 1 x Limb Ozone Bag with in/outlet, 1 x MnO3 Ozone Destruct Unit, 2 x 60ml Syringes, 6 x Luerlock connectors AND MORE!


Ms, J. D., Menéndez-cepero, S., Macías-abraham, C., & Ms, L. F. (2017). Systemic Ozone Therapy by Rectal Insufflation for Immunoglobulin A Deficiency, 29–35.

Technology, H., Unit, A., Division, M. D., & Health, M. O. F. (2005). Ozone therapy, 6, 35. https://doi.org/10.1007/s00234-011-0930-7

Rubin, M. B. (2001). The history of ozone. The Schönbein period, 1839–1868. Bull. Hist. Chem, 26(1), 40–56. Retrieved from http://www.scs.illinois.edu/~mainzv/HIST/bulletin_open_access/v26-1/v26-1 p40-56.pdf%5Cnpapers3://publication/uuid/44D0A126-1E41-457A-A420-B25B9D314C03

V., B. (2002). Side Effects and Contraindications of Ozone Therapy. Springer, Dordrecht. https://doi.org/https://doi.org/10.1007/978-94-015-9952-8_21

Bocci, V., Zanardi, I., & Travagli, V. (2011). Oxygen / ozone as a medical gas mixture . A critical evaluation of the various methods clarifies positive and negative aspects. Medical Gas Research, 1(1), 6. https://doi.org/10.1186/2045-9912-1-6


Smith, N., Wilson, A., Gandhi, J., Vatsia, S., & Khan, S. (2017). Ozone therapy: An overview of pharmacodynamics, current research, and clinical utility. Medical Gas Research, 7(3), 212. https://doi.org/10.4103/2045-9912.215752

Bocci, V. (1996). Ozone as a bioregulator. Pharmacology and toxicology of ozonetherapy today. Journal of Biological Regulators and Homeostatic Agents.

Plessis, L. H., Westhuizen, F. H. Van Der, & Kotze, H. F. (2007). The effect of blood ozonation on mitochondrial function and apoptosis of peripheral blood mononuclear cells in the presence and absence of plasma antioxidants. Journal of Biotechnology, 6(August), 1763–1769.

Sagai, M., & Bocci, V. (2011). Mechanisms of Action Involved in Ozone Therapy: Is healing induced via a mild oxidative stress? Medical Gas Research, 1(1), 29. https://doi.org/10.1186/2045-9912-1-29

Mccabe, E. (n.d.). Ozone Therapies for AIDS.

Jr, P. W., Mcdunn, J. E., Wentworth, A. D., Takeuchi, C., Nieva, J., Jones, T., … Lerner, R. A. (2002). Evidence for Antibody-Catalyzed Ozone Formation in Bacterial Killing and Inflammation, 298(December), 2195–2200.

Burleson, G. R., Murray, T. M., Burleson, G. R., Murray, T. M., & Pollard, M. (1975). Inactivation of Viruses and Bacteria by Ozone , With and Without Sonication Inactivation of Viruses and Bacteria by Ozone , With and Without Sonication.

Diseases, S. O. (1996). Does Ozone Therapy Normalize the Cellular Redox Balance ? Implications for the Therapy of Human Immunodeficiency Virus Infection and Several Other Diseases, 150–154.

Review, S. (2009). Oxygen-Ozone Therapy in Medicine : An Update, 373–376. https://doi.org/10.1159/000236365

Sunday, S. L. (2004). How Ozone Affects Bacteria , Fungus , Molds And Viruses The Effects of Ozone on Pathogens, (October), 3–5.

Fathi, A. M., Mawsouf, M. N., Viebahn-hänsler, R., Fathi, A. M., Mawsouf, M. N., Viebahn-hänsler, R., … Viebahn-hänsler, R. (2016). Ozone : Science & Engineering The Journal of the International Ozone Association Ozone Therapy in Diabetic Foot and Chronic , Nonhealing Wounds Ozone Therapy in Diabetic Foot and Chronic , Nonhealing Wounds, 9512(June). https://doi.org/10.1080/01919512.2012.718700

Mawsouf, M. N., Tanbouli, T. T., Mawsouf, M. N., & Tanbouli, T. T. (2016). Ozone : Science & Engineering The Journal of the International Ozone Association Ozone Therapy in Patients with Viral Hepatitis C : Ten Years ’ Experience Ozone Therapy in Patients with Viral Hepatitis C : Ten Years ’ Experience, 9512(June). https://doi.org/10.1080/01919512.2012.720161

Elvis, A. M., & Ekta, J. S. (2016). Ozone therapy : A clinical review, 2(1), 66–70. https://doi.org/10.4103/0976-9668.82319

Calunga, J. L., Menéndez, S., León, R., Chang, S., Balbín, A., Zayas, J., … García, P. (2016). Ozone : Science & Engineering The Journal of the International Ozone Association Application of Ozone Therapy in Patients with Knee Osteoarthritis Application of Ozone Therapy in Patients with Knee Osteoarthritis, 9512(June). https://doi.org/10.1080/01919512.2012.719120

Fontes, B., Maria, A., Heimbecker, C., Brito, G. D. S., Costa, S. F., & Heijden, I. M. Van Der. (2012). Effect of low-dose gaseous ozone on pathogenic bacteria. https://doi.org/10.1186/1471-2334-12-358

Viebahn-hänsler, R., Sonia, O., Fernández, L., Fahmy, Z., Sonia, O., Fernández, L., … Fahmy, Z. (2016). Ozone : Science & Engineering The Journal of the International Ozone Association Ozone in Medicine : The Low-Dose Ozone Concept — Guidelines and Treatment Strategies Ozone in Medicine : The Low-Dose Ozone Concept — Guidelines and Treatment Strategies, 9512(June). https://doi.org/10.1080/01919512.2012.717847

Díaz-soto, M. T., Pérez, A. F., Vaillant, J. D., Mallok, A., Viebahn-hänsler, R., Cepero, S. M., … Fernández, L. (2012). Ozone : Science & Engineering The Journal of the International Ozone Association Ozone Therapy Ameliorates Nervous System Disorders and Oxidative Stress in Patients During Ethanol Withdrawal — A Pilot Study Ozone Therapy Ameliorates Nervous System Disorde, 9512(June 2016). https://doi.org/10.1080/01919512.2012.717858

Ahmed M. Fathi, M. N. M. & R. V.-H. (2012). Ozone Therapy in Diabetic Foot and Chronic, Nonhealing Wounds. Ozone: Science & Engineering: The Journal of the International Ozone Association, 438–450. https://doi.org/10.1080/01919512.2012.718700

Bocci, V. A. (2006). Scientific and medical aspects of ozone therapy. State of the art. Rivista Italiana Di Ossigeno-Ozonoterapia. https://doi.org/10.1016/j.arcmed.2005.08.006

Sunnen, G. V. (2005). The Utilization of Ozone for External Medical Applications.

Travagli, V., Zanardi, I., Valacchi, G., & Bocci, V. (2010). Ozone and ozonated oils in skin diseases: A review. Mediators of Inflammation. https://doi.org/10.1155/2010/610418


SHOP     |     PEMF     |     OZONE     |     LASER     |     RIFE     |     HYPER-SAUNA       Advertisement